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Volume 2, #11, March 1997
State-of-the-Art in the Management of Cancer
Ovarian Cancer-part 1
Epidemiology, Etiology And Pathogenesis

Epidemiology

Molecular Genetics

  • Hereditary Ovarian Tumors
  • Sporadic Ovarian Tumors

Etiology

  • Reproductive and Endocrine Factors
  • Environmental Factors
  • Dietary Factors

Pathogenesis

Meeting Coverage

A Report from the Fifth International Conference on Gene Therapy of Cancer

November 14-16, 1996, San Diego, CA

Oligonucleotide-based Cancer Therapeutics

  • Mechanisms of Action
  • Antisense Approaches Based on Phosphorothioate Oligonucleotides
  • True Antisense Agents
  • Non-antisense Effects
  • Antisense Regulation of Cell Proliferation Through the Mitogen-Activated Protein (MAP) Kinase Pathway
  • Ribozyme Reagents Targeting Multi-drug Resistance
  • Antisense Bcl-2 Therapy for Non-Hodgkin's Lymphoma
  • Down-regulation of Metallothionein
  • Prostate Cancer Therapy Using an RNP Polymerase I-targeted Ribozyme
  • Ribozyme-mediated Inhibition of Telomerase Activity

p53

  • Viral-mediated p53 Gene Replacement Therapy
  • Clinical Trials of p53 Gene Therapy for Hepatic Cancer
  • Evaluation of the Bystander Effect in Adenovirus-mediated p53 Gene Therapy
  • p53 Gene Replacement: Choose your Molecule with Caution

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