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Future Oncology - Technology, Products, Markets, and Service Opportunities

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FUTURE ONCOLOGY - TECHNOLOGY, PRODUCTS, MARKETS, AND SERVICE OPPORTUNITIES IN THE CANCER FIELD

FUTURE ONCOLOGY
Volume 7 #6/7 August 31, 2003


Meeting Coverage

RANDOMIZED CLINICAL TRIALS WITH NOVEL ANTICANCER AGENTS
FROM THE 2003 MEETING OF THE AMERICAN SOCIETY OF CLINICAL ONCOLOGY (ASCO)

INCREASED EMPHASIS IN ALL ASPECTS OF CLINICAL TRIALS IN ONCOLOGY
  • Efforts to Increase Patient Participation
  • Streamlining Cancer Drug Development
  • Reporting and Registering Clinical Trials
RANDOMIZED AND LARGE CLINICAL TRIALS IN ONCOLOGY
  • Ethics of Large Clinical Trials in Oncology
  • The Impact of Pharmacogenomics
  • Design of Clinical Trials for New Molecularly Targeted Compounds
  • Randomized Discontinuation Design
  • Relationship Between Response Rate and Survival
OVERSIGHT IN CLINICAL DEVELOPMENT OF ANTICANCER DRUGS
  • Centralized Review Boards
  • Conflict of Interest Guidelines
DRUG COMBINATION STRATEGIES IN ONCOLOGY
  • Colorectal Cancer
  • Lung Cancer
  • Mesothelioma
  • Prostate Cancer
  • Biochemotherapy in Metastatic Melanoma
MARKETS OF NEW ANTICANCER DRUGS

NOVEL AGENTS IN RANDOMIZED CLINICAL TRIALS REPORTED AT ASCO03
  • -941
  • Atrasentan
  • Bevacizumab
  • BMS-247550
  • CeaVac
  • CCI-779
  • Cetuximab
  • Gefitinib
  • Irofulven
  • LY900003
  • Pemetrexed
  • Provenge
  • PSA-based Vaccine
  • Rubitecan
  • Satraplatin
  • Thalidomide
  • Tirapazamine

LIST OF EXHIBITS

Exhibit 1 - Novel Anticancer Agents in Ongoing or Recently Completed Single-agent or Combination, Randomized, Phase III Clinical Trials

Exhibit 2 - Worldwide Markets of Selected Novel Anticancer Agents with Revenues of >$100 Million Introduced Since 1990

Exhibit 3 - Anticancer Agents Granted Accelerated Approval by the FDA (1996-2003)


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